SADI-S (Single Anastomosis Duodeno-Ileal) is a type of obesity surgery. Doctors use this operation as an effective option for treating obesity and type 2 diabetes. This procedure aims to alter the anatomy of the stomach and intestines to promote weight loss and metabolic improvement.

What is SADI-S?

SADI-S, or the Single Anastomosis Duodenal Switch Surgery, introduced to medical literature by Dr. Scorpinaro and safely practiced in America for about 20 years, is an alternative method used in obesity treatment. It is known for its metabolic effects derived from “duodenal switch and biliopancreatic diversion” surgeries.

Although this surgery has the same effects as the classic “Duodenal Switch” surgery, it involves only one anastomosis (intestinal connection), thus carrying fewer risks.

In this surgical method, the stomach is typically fashioned into a tube shape. Then, the intestines, which primarily function to absorb ingested food and are about 5-6 meters long, are bypassed, reducing the absorption area to 2.5 meters. Importantly, no part of the intestine is removed from the body during this operation. The area exposed to food is shortened, and the remaining part of the intestine stays in place, ensuring the continuation of normal bile and pancreatic flow.


What Advantages Does Surgery Offer?

This technique restricts intake with a sleeve stomach and reduces absorption with a bypass, providing a feeling of fullness and reducing appetite. It also triggers the secretion of the GLP-1 hormone, thus helping control the appetite center in the brain and emotional hunger. If eating disorders are not managed, issues like diarrhea, malabsorption, and loss of proteins and vitamins can occur.Therefore, the long-term risk of weight gain should not be overlooked.

Compared to other bypasses, SADI-S preserves the pyloric muscle, which reduces the risk of “Dumping Syndrome.” Dumping Syndrome is characterized by sudden weakness, dizziness, sweating, and nausea after eating. In classic bypasses, it starts within 10 minutes and lasts up to an hour. However, with the pyloric muscle intact in SADI-S, this syndrome does not occur.

In communities with a high risk of stomach cancer, viewing with endoscopy is crucial. In Roux-en-Y and Mini-Gastric Bypass, the blind spot of the stomach cannot be seen with endoscopy, but this is not an issue with SADI-S. For diabetic patients, SADI-S provides better long-term sugar control compared to a sleeve stomach.

This method changes the anatomy and physiology more than other types of bypass, compared to a sleeve stomach. The risk of vitamin deficiency is lower than with the classic DS. Like other bypasses, patients may experience foul-smelling diarrhea in the early stages.